MARCO COSENTINO LAGOMARSINO
Università di Milano
A model of self-organization of microtubules driven by molecular
motors
Autori:
Bruno Bassetti(*), Marco Cosentino Lagomarsino(*), Patrizia Jona(**).
(*)Università degli Studi di Milano - Dip. di Fisica;
(**)Politecnico di Milano - Dip. di Fisica.
Recent 'in vitro' experiments show that ensembles of cytoskeletal
filaments (microtubules) and molecular motors are able to self-organize.
We propose a two-dimensional model in which two kinds of dynamics are
competing. The first one is generated by an orientational interaction,
while the second one is a local drive dependent on
microtubule polarity. A configuration dependent driving field is
then present.
Applying a molecular field approximation to microscopic dynamics, we are
able to derive continuum equations. A study of the solutions of these
equations shows the existence of nonequilibrium steady states in various
regions of the parameter space.
The presence and stability of states of such nature are investigated in
terms of entropy production. Numerical simulations confirm our results.